No plausible mechanism to explain allegations that aspartame may prevent weight loss in humans

ISA response to mice study by researchers at Massachusetts General Hospital The mechanism suggested by researchers at Massachusetts General Hospital claiming that aspartame might not promote weight loss is simply not biologically plausible. On the contrary, strong evidence from clinical studies in humans supports the helpful role of low calorie sweeteners, such as aspartame, in reduced […]

ISA refutes allegations from the Ramazzini Institute

Brussels, 7th November 2016: The International Sweeteners Association (ISA) refutes the conclusions in a publication by Soffritti et al. 1 reporting findings from a study in mice, completed in 2012, claiming that sucralose causes cancer. These conclusions, based on one single study, are totally inconsistent with the significant body of scientific research demonstrating that this ingredient […]

Evidence does not support a relationship between diet drinks and diabetes

ISA statement in response to the study by Karolinska Institute, Sweden, on diet drinks and diabetes The International Sweeteners Association (ISA) having reviewed this paper concludes that there is no evidence that the consumption of low calorie sweetened drinks increases the risk of developing diabetes, as a new observational study 1 by Karoliska Institute, Sweden, claims. It is […]

Low calorie sweeteners do not affect fertility in women

ISA statement in response to a study to be presented at the American Society for Reproductive Medicine congress in Salt Lake City The International Sweeteners Association (ISA) strongly refutes the findings of a new unpublished study and, importantly, supports that this observational study does not show that low calorie sweeteners are related to low fertility rates. […]

Childhood obesity increasing trends can be reversed

ISA statement in support of World Obesity Day 2016 “Ending childhood obesity” Celebrated for the second time since its official launch by the World Obesity Federation last year, World Obesity Day aims to stimulate and support practical actions that will help people achieve and maintain a healthy weight and reverse the global obesity crisis. With the prevalence of infant, […]

Bias and limitations in a systematic review by mandrioli et al raise serious concerns about its conclusions regarding industry-supported research on low calorie sweeteners

ISA statement in response to the systematic review by Mandrioli et al The International Sweeteners Association (ISA) strongly refutes the misleading and biased conclusions in an article by Mandrioli et al in Plos One claiming that industry-supported research on low calorie sweetened beverages and weight outcomes is more likely to show favourable results. The authors […]

Study from York University does not show a link between aspartame intake and glucose intolerance

ISA statement in response to the study published by Kuk and Brown, York University, Canada regarding aspartame intake and glucose intolerance in obese individuals The International Sweeteners Association (ISA) has examined the results of the observational study by Kuk and Brown entitled “Aspartame intake is associated with greater glucose intolerance in individuals with obesity”1 published […]

Evidence does not prove any direct relationship between consumption of diet drinks during pregnancy and higher infant weight

ISA statement in response to the study published in JAMA Pediatrics regarding diet drinks’ consumption in pregnancy and infant BMI The International Sweeteners Association (ISA) has reviewed the results of the observational study by Azad et al. entitled ‘’Association between artificially sweetened beverage consumption during pregnancy and infant body mass index (BMI)’ published on 9th […]

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