A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis
Abstract The discovery of gut sweet taste receptors has led to speculations that non-nutritive sweeteners, including sucralose, may affect glucose control. A double-blind, parallel, randomized clinical trial, reported here and previously submitted to regulatory agencies, helps to clarify the role of sucralose in this regard. This was primarily an out-patient study, with 4-week screening, 12-week […]
American Diabetes Association® 2017 Standards of Medical Care in Diabetes: Lifestyle management
Abstract American Diabetes Association® Releases 2017 Standards of Medical Care in Diabetes. Comprehensive, annual guide includes new and updated recommendations to safeguard the physical and psychological health of people with diabetes. The Standards are established and revised annually by a Professional Practice Committee. No abstract available. Summary Nutrition therapy is a fundamental aspect of diabetes […]
Sugar-Sweetened Beverage but Not Diet Soda Consumption Is Positively Associated with Progression of Insulin Resistance and Prediabetes
Abstract Background: Previous studies have shown an inconsistent relation between habitual beverage consumption and insulin resistance and prediabetes. Objective: The objective of the present study was to test the hypothesis that the consumption of sugar-sweetened beverages (SSBs), rather than diet soda, is associated with long-term progression of insulin resistance and the development of prediabetes. Methods: We analyzed the […]
Sweetened beverage intake and risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes
Abstract OBJECTIVE: Sweetened beverage intake is associated with increased risk of type 2 diabetes, but its association with autoimmune diabetes is unclear. We aimed to investigate sweetened beverage intake and risk of latent autoimmune diabetes in adults (LADA); autoimmune diabetes with features of type 2 diabetes. DESIGN/METHODS: Data from a Swedish population-based study was used, including incident […]
Effects of the non-nutritive sweeteners on glucose metabolism and appetite regulating hormones: Systematic review of observational prospective studies and clinical trials
Abstract Background: The effects of non-nutritive sweeteners (NNS) on glucose metabolism and appetite regulating hormones are not clear. There is an ongoing debate concerning NNS use and deleterious changes in metabolism. Objectives: The aim of this review is to analyze the scientific available evidence regarding the effects of NNS on glucose metabolism and appetite regulating hormones. Data Sources and […]
Consensus statement on benefits of low-calorie sweeteners
Summary A Panel of independent experts was convened to discuss the evidence for benefits of Low Calorie sweeteners (LCS) in five key areas. The Consensus Statement represents an agreed position by all members of the Panel. Appetite Low calorie sweeteners do not increase appetite and have no discernible effect on satiety. Preference for sweetness is […]
Impact of diet composition on blood glucose regulation
Abstract Nutritional management of blood glucose levels is a strategic target in the prevention and management of type 2 diabetes mellitus (T2DM). To implement such an approach, it is essential to understand the effect of food on glycemic regulation and on the underlying metabolic derangements. This comprehensive review summarizes the results from human dietary interventions […]
The role of low-calorie sweeteners in diabetes
Abstract As the incidence and prevalence of type 2 diabetes continue to rise, the identification of components that contribute to or are associated with this disease has become a priority. One of the main factors that has been linked to type 2 diabetes is excessive weight gain, and reduction in weight has been recommended for […]
Nonnutritive sweeteners: current use and health perspectives: a scientific statement from the American Heart Association and the American Diabetes Association
Summary Limiting added sugars is an important strategy for supporting optimal nutrition and healthy weights, as concluded in the 2009 American Heart Association scientific statement “Dietary Sugars Intake and Cardiovascular Health.” Monitoring carbohydrate intake, which includes limiting added sugars, is also a key strategy to achieve glycemic control as published in the American Diabetes Association […]
Short-Term Impact of Sucralose Consumption on the Metabolic Response and Gut Microbiome of Healthy Adults
Abstract Sucralose is an artificial non-nutritive sweetener used in foods aimed to reduce sugar and energy intake. While thought to be inert, the impact of sucralose on metabolic control has shown to be the opposite. The gut microbiome has emerged as a factor shaping metabolic responses after sweetener consumption. We examined the short-term effect of […]