A critical appraisal of the WHO reviews of aspartame
Highlights Following a comprehensive safety assessment of all available evidence, the Joint FAO/WHO Expert Committee on Food Additives (JECFA), reconfirmed the safety of aspartame and re-affirmed the Acceptable Daily Intake. As part of its comprehensive assessment, JECFA examined recent conclusions of the International Agency for Research on Cancer (IARC), which classified aspartame as “possibly carcinogenic […]
ISA scientific response to the World Health Organization (WHO) guideline on use of non-sugar sweeteners
The WHO guideline on use of non-sugar sweeteners risks hindering global efforts to stem the rise of non-communicable diseases (NCDs) Highlights Scientifically rigorous studies have repeatedly demonstrated the benefits of low/no calorie sweeteners in calorie reduction and weight control, dental health and diabetes management The WHO guideline lacks scientific rigour as it is not […]
No rise in blood glucose with low/no calorie sweetened beverages, like water
New systematic review of clinical trials confirms benefits of low/no calorie sweeteners when compared to sugars Highlights A new systematic review of controlled clinical trials found that low/no calorie sweetened beverage consumption has a neutral impact on blood glucose and endocrine responses, contrary to effects seen with sugar-sweetened beverages The (lack of) impact of low/no […]
Science news on low/no calorie sweeteners: 2022 year in review
Highlights: Benefits of low/no calorie sweeteners in reducing sugars and calorie intakes and assisting with weight loss are confirmed in 2022 systematic reviews and meta-analyses of randomised controlled trials (RCTs) Low/no calorie sweetened beverages may be associated with cardiometabolic benefit when used to replace sugar-sweetened beverages New studies confirm that low/no calorie sweeteners’ intake is […]
Addressing reverse causality in observational research is critical to establish reliable associations between low/no calorie sweeteners and cardiometabolic health
Results of a systematic review and meta-analysis of prospective cohort studies that model intake of sweeteners as change or substitutions to mitigate the influence of reverse causality Highlights: Reverse causality is a major source of bias in observational studies investigating associations between low/no calorie sweeteners and health outcomes By including prospective cohort studies that […]
The WHO recommendation for non-sugar sweeteners use is not supported by the collective evidence
A critical appraisal of the draft WHO guideline on use of non-sugar sweeteners Highlights Evidence from higher quality research reviewed recently by WHO supports the useful role of low/no calorie sweeteners in sugar and energy reduction and, in turn, in weight loss, despite a draft recommendation today suggesting against their use in weight control […]
Low/no calorie sweeteners can help in calorie reduction and weight loss, according to a new WHO-supported review
A critical appraisal of the systematic review by Rios-Leyvraz and Montez on health effects of low/no calorie sweeteners Highlights Results of the new WHO-supported study confirm that low/no calorie sweeteners may be effective at assisting with weight loss, when used in place of sugars resulting in calorie reduction Evidence from controlled clinical trials supports no […]
New study shows helpful role of substituting sugary drinks with low/no calorie sweetened beverages for people living with overweight or obesity
Outcomes of a systematic review and network meta-analysis of clinical trials conducted by the Diabetes and Nutrition Study Group of the European Association for the Study of Diabetes (EASD) to inform the EASD Clinical Practice Guidelines for Nutrition Therapy Highlights A new systematic review and meta-analysis of randomised controlled trials (RCTs) confirms a beneficial role […]
Science news on low/no calorie sweeteners (Part B): 2021 scientific events in review
Highlights: Data from newly published studies conducted in Argentina, Chile, and Peru show that the intake levels of common low/no calorie sweeteners are below their respective Acceptable Daily Intakes (ADIs). Scientific experts suggest that the collective evidence supports the assertion that when used in place of sugar, low/no calorie sweeteners may help in weight management. […]
Science news on low/no calorie sweeteners (Part A): 2021 in review
Highlights: New studies and reports published in 2021 confirm the safety and role of low/no calorie sweeteners in sugar and calorie reduction, which in turn can help in weight management. The use of low/no calorie sweeteners in place of sucrose may also have a promising prospect in caries management, according to the authors of a […]