Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories
Abstract Calories from any food have the potential to increase risk for obesity and cardiometabolic disease because all calories can directly contribute to positive energy balance and fat gain. However, various dietary components or patterns may promote obesity and cardiometabolic disease by additional mechanisms that are not mediated solely by caloric content. Researchers explored this […]
Nonnutritive sweeteners in weight management and chronic disease: A review
Abstract Objective: The objective of this review was to critically review findings from recent studies evaluating the effects of nonnutritive sweeteners (NNSs) on metabolism, weight, and obesity-related chronic diseases. Biologic mechanisms that may explain NNS effects will also be addressed. Methods: A comprehensive review of the relevant scientific literature was conducted. Results: Most cross-sectional and prospective cohort studies […]
Sweet taste exposure and the subsequent acceptance and preference for sweet taste in the diet: systematic review of the published literature
Abstract BACKGROUND: There are consistent, evidence-based global public health recommendations to reduce intakes of free sugars. However, the corresponding evidence for recommending reduced exposure to sweetness is less clear. OBJECTIVE: Our aim was to identify and review the published evidence investigating the impact of dietary exposure to sweet-tasting foods or beverages on the subsequent generalized acceptance, preference, […]
Beverages containing low energy sweeteners do not differ from water in their effects on appetite, energy intake and food choices in healthy, non-obese French adults
Abstract The usefulness of replacement of caloric sugars by low-calorie sweeteners (LCS) for weight management has been questioned on the grounds that the uncoupling of LCS sweet taste and dietary energy may confuse physiological mechanisms, leading potentially to higher energy and sugar intake. The aim of the present study was to determine whether LCS beverages […]
Use of table sugar and artificial sweeteners in Brazil: National Dietary Survey 2008-2009
Abstract The study aimed to describe the use of table sugar and artificial sweeteners (AS) in Brazil. A representative sample (n = 32,749) of individuals aged > 10 years was examined from the Brazilian National Dietary Survey (2008–2009). Participants reported whether they use table sugar, AS, both, or none as sweeteners for their foods and […]
The role of low-calorie sweeteners in the prevention and management of overweight and obesity: evidence v. conjecture
Abstract By virtue of reducing dietary energy density, low-calorie sweeteners (LCS) can be expected to decrease overall energy intake and thereby decrease body weight. Such effects will be limited by the amount of sugar replaced by LCS, and the dynamics of appetite and weight control (e.g., acute compensatory eating, and an increase in appetite and […]
Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
Abstract BACKGROUND: Nonnutritive sweeteners, such as aspartame, sucralose and stevioside, are widely consumed, yet their long-term health impact is uncertain. We synthesized evidence from prospective studies to determine whether routine consumption of non-nutritive sweeteners was associated with long-term adverse cardiometabolic effects. METHODS: We searched MEDLINE, Embase and Cochrane Library (inception to January 2016) for randomized […]
Effects of nonnutritive sweeteners on body weight and BMI in diverse clinical contexts: Systematic review and meta-analysis
Abstract There is an ongoing debate about the possible influences of nonnutritive sweeteners (NNS) on body weight. We conducted a systematic review and meta?analysis of randomized controlled trials (RCTs) with NNS to assess their impact on body weight. We systematically searched for RCTs at least 4 weeks in duration, evaluating the effect of NNS on […]
Variazione personale di preferenza per la dolcezza: Effetti dell’età e dell’obesità
Abstract ELEMENTI DI BASE L’uso di dolcificanti non nutritivi (NNS), che forniscono gusto dolce con pochissime/zero calorie, è aumentato, ma i dati relativi alle differenze di risposte edoniche nei bambini agli NNS rispetto agli zuccheri nutritivi o delle risposte edoniche degli adulti sono limitate. METODI: I livelli preferiti di sucrosio e di sucralosio NNS sono […]
Effetti metabolici dell’aspartame nell’età adulta: analisi sistematica e meta-analisi di sperimentazioni cliniche randomizzate
Abstract ELEMENTI DI BASE I dati sui pericoli e i benefici associati al consumo di aspartame, dolcificante non nutritivo consumato in tutto il mondo, sono ancora controversi. L’analisi e la metanalisi sistematica delle sperimentazioni controllate randomizzate intendevano valutare l’effetto del consumo di aspartame sui parametri metabolici relativi al diabete e all’obesità. METODI: La ricerca è […]
