Systematic review and evaluation of aspartame carcinogenicity bioassays using quality criteria
Abstract The current review assessed cancer studies of aspartame based on a quality appraisal using the Klimisch grading system. Nine studies having complete histopathology were included: three 2-year studies by Searle; three transgenic mice studies by the NTP; three lifetime studies by the Ramazzini Institute. A tenth study limited to brain tumors was not rated. […]
Dietary intakes of six intense sweeteners by Irish adults
Abstract This research investigated the intakes of six intense sweeteners; acesulfame-K (E950), aspartame (E951), cyclamate (E952), saccharin (E954), sucralose (E955) and steviol glycosides (E960) in the diets of Irish adults, using data from the National Adult Nutrition Survey (NANS). A food label survey which included products currently available on the Irish market supplemented the analysis. […]
Low calorie sweeteners in childhood: analysis of the scientific evidence (Edulcorantes no calóricos en la edad pediátrica: análisis de la evidencia científica)
Abstract Artificial sweeteners are food additives with the technological function of conferring a sweet taste on foods, but with a very low or zero nutritional energy value. There are doubts among consumers about the health risks that might be associated with the use of non-caloric sweeteners. In the pediatric community, there is interest in the […]
Aspartame: A review of genotoxicity data
Abstract Aspartame is a methyl ester of a dipeptide of aspartic acid and phenylalanine. It is 200× sweeter than sucrose and is approved for use in food products in more than 90 countries around the world. Aspartame has been evaluated for genotoxic effects in microbial, cell culture and animal models, and has been subjected to […]
Re-evaluation of acesulfame K with reference to the previous SCF opinion of 1991
Abstract No abstract available. Summary In its re-evaluation of acesulfame K in 2000, the Scientific Committee on Food (SCF) of the European Commission, reaffirmed its previous conclusions that acesulfame potassium (acesulfame K) is safe and without mutagenic or carcinogenic potential. Furthermore, acesulfame K does not induce any other effects of toxicological significance. Furthermore, the Committee […]
Opinion of the Scientific Committee on Food on sucralose
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission concluded that sucralose is safe as a sweetener for general food use and that a full ADI of 0-15mg/kg bw can be established, based on application of a 100-fold safety factor to the overall NOEL of 1500mg/kg bw/day. There is […]
Revised opinion on cyclamic acid and its sodium and calcium salts
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission confirmed that cyclamic acid and its salts are safe and established a full ADI of 0-7 mg/kg bw, expressed as cyclamic acid, for cyclamic acid and its sodium and calcium salts in 2000. Cyclamic acid and its sodium and calcium […]
Opinion on saccharin and its sodium, potassium and calcium salts
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission established a full ADI of 0-5 mg/kg bw for sodium saccharin in 1995 and reconfirmed its safety. Saccharin and its sodium, potassium and calcium salts were first evaluated by the Scientific Committee for Food (SCF) in 1977 when a temporary […]
Non-nutritive Sweeteners for Diabetes Mellitus
Abstract Background: Products sweetened with non-nutritive sweeteners (NNS) are widely available. Many people with type 1 or type 2 diabetes use NNS as a replacement for nutritive sweeteners to control their carbohydrate and energy intake. Health outcomes associated with NNS use in diabetes are unknown. Objectives: To assess the effects of non-nutritive sweeteners in people […]
Nutrition Therapy for Adults with Diabetes or Prediabetes: A Consensus Report
Summary This Consensus Report of the American Diabetes Association (ADA) is intended to provide clinical professionals with evidence-based guidance about individualizing nutrition therapy for adults with diabetes or prediabetes. Nutrition counselling that works toward improving or maintaining glycaemic targets, achieving weight management goals, and improving cardiovascular risk factors (e.g., blood pressure, lipids, etc.) within individualized […]