ISA statement on new study on sweeteners and cognitive health
Following the publication of the new study, “Not so sweet: Some sugar substitutes linked to faster cognitive decline,” in Neurology on 3 September 2025, the International Sweeteners Association (ISA) urges a careful interpretation of its findings. While the study has garnered media attention, it is essential to place its results within the broader, established scientific consensus on sweeteners safety.
Food safety authorities confirm aspartame’s safety
Brussels, 15 July 2025: The International Sweeteners Association (ISA) urges caution when interpreting results of the recent study by Meng et al on aspartame. This is a small mice study with limited statistical power, whose results should be considered preliminary and cannot be directly translated to humans. Aspartame has been the subject of an overwhelming number […]
EFSA reaffirms the safety of Neotame
ISA welcomes the new EFSA scientific opinion on Neotame Brussels, 4th July 2025: The International Sweeteners Association (ISA) welcomes the European Food Safety Authority (EFSA) opinion, published today, which unequivocally confirms that neotame is rigorously assessed and safe for use in foods and beverages.1 Neotame is one of the 11 low/no calorie sweeteners approved for use […]
Safety of acesulfame K reconfirmed by EFSA
The European Food Safety Authority reconfirms acesulfame K’s safety after conducting a thorough, comprehensive and scientifically rigorous review. These conclusions are consistent with a history of safe use, confirmed by global and national food safety agencies, for more than thirty years. Brussels, 30th April 2025: The International Sweeteners Association (ISA) welcomes the European Food Safety […]
ISA statement on draft regulations proposed at state level in the United States of America affecting Low/No Calorie Sweeteners
Updated on 26 May 2025 Since the beginning of 2025, several state level bills in the USA have been proposed targeting different food additives, including low/no calorie sweeteners (LNCS) and often based on misinformation on their approval status in certain countries or misinterpretation of scientific evidence. The International Sweeteners Association (ISA) would like to remind […]
Low/no calorie sweeteners do not increase type 2 diabetes’ risk
Brussels, 9th April 2025: In light of new observational research on food additive mixtures and risk of T2 diabetes, the International Sweeteners Association (ISA) highlights existing evidence indicating that consuming low/no calorie sweeteners does not affect glucose control or increase the risk of type 2 diabetes. The present analysis of the NutriNet-Santé cohort data does […]
Low/no calorie sweeteners have a role to play in reducing sugar and calorie intake and aiding weight control
Brussels, 2nd April 2025: Responding to the UK Scientific Advisory Committee on Nutrition (SACN) statement on the WHO guideline on non-sugar sweeteners, the International Sweeteners Association (ISA) reconfirms low/no calorie sweeteners’ (LNCS) role in helping address the global obesity crisis. While reviewing the WHO guideline on LNCS, SACN pointed to differences in the WHO methods […]
Sucralose has no impact on appetite
Brussels, 28th March 2025: Contrary to what suggested by a new study from the University of Southern California, it is important to highlight that sucralose does not affect appetite. The study by Chakravartti et al. does not provide evidence that sucralose disrupts appetite regulation or increases energy or food intake. In fact, the study results […]
Aspartame does not affect heart health
Brussels, 20th February 2025: Contrary to what is reported in the animal study by Wu and colleagues, the International Sweeteners Association (ISA) points to the available scientific evidence showing that aspartame does not affect heart health. Human clinical studies consistently confirm no adverse impact of aspartame on glucose control, blood lipids, blood pressure, or other […]
Low/no calorie sweeteners’ benefits in food processing: going beyond the concept of Ultra-Processed Food
Brussels, December 2024 Today, families have more safe and affordable foods and drinks thanks to processing, whether it’s done at home with products like canned vegetables and frozen foods, or on an industrial scale. Food processing can also provide public health benefits, for example recipe changes to certain products to help with specific dietary needs […]