Safety

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Estimation of exposures to non-nutritive sweeteners from consumption of tabletop sweetener products: a review

Author(s): David R. Tennant
Publication Name: Food Additives & Contaminants: Part A, DOI: 10.1080/19440049.2019.1566784.
Publication Year: 2019

Table-top sweetener products are preparations of low/no calorie sweeteners, which may contain other food additives and/or food ingredients and which are sold as a substitute for sugars. Reliable estimation of intake of low/no calorie sweeteners in...

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Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota

Author(s): Lobach AR, Roberts A, Rowland IR.
Publication Name: Food and Chemical Toxicology (2019), doi: https://doi.org/10.1016/j.fct.2018.12.005.
Publication Year: 2018

This extensive review of the scientific literature concluded that current studies investigating the impact of low calorie sweeteners on gut microbiota show no evidence of any adverse effect on the gut microbiota at doses of low calorie sweeteners...

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Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance)

Author(s): Guercio BJ, Zhang S, Niedzwiecki D, Li Y, Babic A, Morales-Oyarvide V, et al.
Publication Name: PLoS ONE 13(7): e0199244. doi.org/10.1371/journal.pone.0199244
Publication Year: 2018

This prospective study of 1,018 patients with stage III colon cancer, enrolled in a National Cancer Institute (NCI)-sponsored clinical trial, showed improved patient outcome in terms of cancer recurrence and survival with increased consumption...

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Ibero–American Consensus on Low- and No-Calorie Sweeteners: Safety, Nutritional Aspects and Benefits in Food and Beverages

Author(s): Serra-Majem L, Raposo A, Aranceta-Bartrina J, Varela-Moreiras G, Logue G, Laviada H, Socolovsky S, Pérez-Rodrigo C, Aldrete-Velasco JA, et al.
Publication Name: Nutrients 2018; 10(7): 818 - doi:10.3390/nu10070818
Publication Year: 2018

Low calorie sweetened foods and beverages could be included in dietary guidelines as alternatives to sugar and sugar-sweetened products, as low calorie sweeteners are safe ingredients that provide sweet taste with low or no calories and with no...

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Low-/No-Calorie Sweeteners: A Review of Global Intakes

Author(s): Martyn D, Darch M, Roberts A, Lee HY, Tian TY, Kaburagi N, Belmar P.
Publication Name: Nutrients 2018, 10(3), 357; doi:10.3390/nu10030357 (This article belongs to the Special Issue ‘Non-Nutritive Sweeteners: A Global Perspective’)
Publication Year: 2018

Having thoroughly reviewed the published literature regarding the intake of the most commonly used low calorie sweeteners globally, Martyn et al concluded that, overall, the studies conducted to determine the exposures of low calorie sweeteners ...

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Systematic review and evaluation of aspartame carcinogenicity bioassays using quality criteria

Author(s): Haighton L, Roberts A, Walters B and Lynch B.
Publication Name: Regulatory Toxicology and Pharmacology, 2018 Jan 12; doi: https://doi.org/10.1016/j.yrtph.2018.01.009
Publication Year: 2018

This systematic review by Haighton et al evaluated aspartame cancer bioassay methods using quality criteria (evaluation against the Klimisch grading system) and concluded that studies with highest rating support that aspartame is not carcinogenic in...

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