Safety

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Low-/No-Calorie Sweeteners: A Review of Global Intakes

Author(s): Martyn D, Darch M, Roberts A, Lee HY, Tian TY, Kaburagi N, Belmar P.
Publication Name: Nutrients 2018, 10(3), 357; doi:10.3390/nu10030357 (This article belongs to the Special Issue ‘Non-Nutritive Sweeteners: A Global Perspective’)
Publication Year: 2018

Having thoroughly reviewed the published literature regarding the intake of the most commonly used low calorie sweeteners globally, Martyn et al concluded that, overall, the studies conducted to determine the exposures of low calorie sweeteners ...

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Systematic review and evaluation of aspartame carcinogenicity bioassays using quality criteria

Author(s): Haighton L, Roberts A, Walters B and Lynch B.
Publication Name: Regulatory Toxicology and Pharmacology, 2018 Jan 12; doi: https://doi.org/10.1016/j.yrtph.2018.01.009
Publication Year: 2018

This systematic review by Haighton et al evaluated aspartame cancer bioassay methods using quality criteria (evaluation against the Klimisch grading system) and concluded that studies with highest rating support that aspartame is not carcinogenic in...

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Dietary intakes of six intense sweeteners by Irish adults

Author(s): Buffini M., Goscinny S., Van Loco J., Nugent AP., Walton J., Flynn A., Gibney MJ and McNulty BA.
Publication Name: Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Dec 6. doi: 10.1080/19440049.2017.1411619. [Epub ahead of print]
Publication Year: 2017

Consistent with findings of studies in other European populations, this research confirms that the intakes of six commonly used intense sweeteners, which include aspartame, acesulfame-K, sucralose, cyclamate, saccharin and steviol glycosides, are al...

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Critical Review of the Current Literature on the Safety of Sucralose

Author(s): Magnuson BA, Roberts A, Nestmann ER
Publication Name: Food and Chemical Toxicology, 2017 May 27. pii: S0278-6915(17)30281-8. doi: 10.1016/j.fct.2017.05.047. [Epub ahead of print]
Publication Year: 2017

Having reviewed the extensive database of studies on sucralose safety, this thorough review of the literature by Magnuson et al., concludes that the collective evidence supports a clear demonstration of safety of use of sucralose as a non-caloric sw...

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Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute

Author(s): EFSA, Panel on Food Additives and Nutrient Sources Added to Food
Publication Name: EFSA Journal 2017;15(5):4784
Publication Year: 2017

The European Food Safety Authority (EFSA) rejected the findings of another questionable study by the Ramazzini Institute and, as expected, reaffirmed sucralose safety, concluding that the available data did not support the conclusions of the author...

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Sugar- and artificially-sweetened beverages and the risks of incident stroke and dementia: A prospective cohort study

Author(s): Pase MP, Himali JJ, Beiser AS, Aparicio HJ, Satizabal CL, Vasan RS, Seshadri S, Jacques PF
Publication Name: Stroke, 2017 May; 48(5): 1139-1146. doi: 10.1161/STROKEAHA.116.016027.
Publication Year: 2017

Using prospective data from the Framingham Offspring Cohort, the findings in Pase et al. cannot provide evidence or a plausible mechanism for a causal link between diet drinks’ consumption and stroke and dementia. Importantly, the suggested associat...

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