Safety

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Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance)

Author(s): Guercio BJ, Zhang S, Niedzwiecki D, Li Y, Babic A, Morales-Oyarvide V, et al.
Publication Name: PLoS ONE 13(7): e0199244. doi.org/10.1371/journal.pone.0199244
Publication Year: 2018

This prospective study of 1,018 patients with stage III colon cancer, enrolled in a National Cancer Institute (NCI)-sponsored clinical trial, showed improved patient outcome in terms of cancer recurrence and survival with increased consumption...

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Ibero–American Consensus on Low- and No-Calorie Sweeteners: Safety, Nutritional Aspects and Benefits in Food and Beverages

Author(s): Serra-Majem L, Raposo A, Aranceta-Bartrina J, Varela-Moreiras G, Logue G, Laviada H, Socolovsky S, Pérez-Rodrigo C, Aldrete-Velasco JA, et al.
Publication Name: Nutrients 2018; 10(7): 818 - doi:10.3390/nu10070818
Publication Year: 2018

Low calorie sweetened foods and beverages could be included in dietary guidelines as alternatives to sugar and sugar-sweetened products, as low calorie sweeteners are safe ingredients that provide sweet taste with low or no calories and with no...

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Low-/No-Calorie Sweeteners: A Review of Global Intakes

Author(s): Martyn D, Darch M, Roberts A, Lee HY, Tian TY, Kaburagi N, Belmar P.
Publication Name: Nutrients 2018, 10(3), 357; doi:10.3390/nu10030357 (This article belongs to the Special Issue ‘Non-Nutritive Sweeteners: A Global Perspective’)
Publication Year: 2018

Having thoroughly reviewed the published literature regarding the intake of the most commonly used low calorie sweeteners globally, Martyn et al concluded that, overall, the studies conducted to determine the exposures of low calorie sweeteners ...

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Systematic review and evaluation of aspartame carcinogenicity bioassays using quality criteria

Author(s): Haighton L, Roberts A, Walters B and Lynch B.
Publication Name: Regulatory Toxicology and Pharmacology, 2018 Jan 12; doi: https://doi.org/10.1016/j.yrtph.2018.01.009
Publication Year: 2018

This systematic review by Haighton et al evaluated aspartame cancer bioassay methods using quality criteria (evaluation against the Klimisch grading system) and concluded that studies with highest rating support that aspartame is not carcinogenic in...

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Dietary intakes of six intense sweeteners by Irish adults

Author(s): Buffini M., Goscinny S., Van Loco J., Nugent AP., Walton J., Flynn A., Gibney MJ and McNulty BA.
Publication Name: Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Dec 6. doi: 10.1080/19440049.2017.1411619. [Epub ahead of print]
Publication Year: 2017

Consistent with findings of studies in other European populations, this research confirms that the intakes of six commonly used intense sweeteners, which include aspartame, acesulfame-K, sucralose, cyclamate, saccharin and steviol glycosides, are al...

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Low calorie sweeteners in childhood: analysis of the scientific evidence (Edulcorantes no calóricos en la edad pediátrica: análisis de la evidencia científica)

Author(s): Guillermo H Wakida-Kuzunoki, Rocío Gabriela Aguiñaga-Villaseñor, Rubén Avilés-Cobián, Manuel Antonio Baeza-Bacab, Brian M Cavagnari, et al.
Publication Name: Revista Mexicana de Pediatría 2017; 84(suppl 1): S3-S23
Publication Year: 2017

Low calorie sweeteners can be safely consumed within the Acceptable Daily Intake (ADI) levels during any stage of life including childhood. There is no evidence of any risks or adverse effects from their use in childhood, or at pregnancy and...

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