With the objective of reviewing the latest scientific evidence on the safety, health effects, and role of low/no calorie sweeteners in sugar reduction, the 1st Latin American Scientific Forum on Sweeteners was held in Mexico in November 2025, bringing together 25 scientific experts from across Latin America and internationally. We spoke with Dr. Angel Gil, Honorary President of the Ibero-American Nutrition Foundation (FINUT) and Professor Emeritus of Biochemistry and Molecular Biology at the University of Granada in Spain, about the Forum’s main conclusions and take away messages.