Assessment of dietary intake of 10 intense sweeteners by the Italian population
Abstract The aim of the present study was to monitor the consumption of foods containing intense sweeteners present on the Italian food market and to investigate whether the Italian general population (aged >3 – 65+) was at risk for exceeding the Acceptable Daily Intake (ADI) of 10 intense sweeteners. A food label survey was performed […]
Biological fate of low-calorie sweeteners
Abstract With continued efforts to find solutions to rising rates of obesity and diabetes, there is increased interest in the potential health benefits of the use of low- and no-calorie sweeteners (LNCSs). Concerns about safety often deter the use of LNCSs as a tool in helping control caloric intake, even though the safety of LNCS […]
Sucralose non-carcinogenicity: A review of the scientific and regulatory rationale
Abstract Regulatory authorities worldwide have found the nonnutritive sweetener, sucralose, to be noncarcinogenic, based on a range of studies. A review of these and other studies found through a comprehensive search of electronic databases, using appropriate key terms, was conducted and results of that review are reported here. An overview of the types of studies […]
Safety of the proposed extension of use of sucralose (E 955) in foods for special medical purposes in young children
Abstract Following a request from the European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion regarding the safety of the extension of use of the food additive sucralose (E 955) when added to dietary food for special medical purpose (FSMP) intended for young children aged […]
Dietary intake of four artificial sweeteners by Irish pre-school children
Abstract In spite of rigorous pre- and post-market reviews of safety, there remains a high level of debate regarding the use of artificial sweeteners in foods. Young children are of particular interest when assessing food chemical exposure as a result of their unique food consumption patterns and comparatively higher exposure to food chemicals on a […]
Dietary intake of non-nutritive sweeteners in type 1 diabetes mellitus children
Abstract The aims of the current cross-sectional study were (1) to assess the intake of aspartame, cyclamate, acesulfame-k, neohesperidine dihydrochalcone, sucralose, saccharin, steviol glycosides and neotame among children with type 1 diabetes mellitus (T1D); (2) to compare the obtained intakes with the respective acceptable daily intake (ADI) values; and (3) to conduct a scenario analysis […]
Scientific Opinion on the safety of the extension of use of thaumatin (E 957)
Abstract Following a request from the European Commission, an exposure assessment was carried out based on the maximum permitted levels (MPLs) authorised in Annex II of Regulation (EC) No 1333/2008 for thaumatin (E 957) and the proposed increase in its use level in flavoured drinks and proposed extension of use in several food categories at […]
Aspartame: A review of genotoxicity data
Abstract Aspartame is a methyl ester of a dipeptide of aspartic acid and phenylalanine. It is 200× sweeter than sucrose and is approved for use in food products in more than 90 countries around the world. Aspartame has been evaluated for genotoxic effects in microbial, cell culture and animal models, and has been subjected to […]
Perspectives on Low Calorie Intense Sweeteners with a Focus on Aspartame and Stevia
Abstract The safety of some food additives/E-numbers, including low calorie (intense) sweeteners (LCS), is constantly the subject of dispute and controversy. However, since LCS have been assigned an acceptable daily intake (ADI) and an E-number following extensive assessment of available safety and toxicological data, consumer safety is assured. These substances have been carefully evaluated, for […]
Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive
Abstract The EFSA ANS Panel provides a scientific opinion on the safety of aspartame (E 951). Aspartame is a sweetener authorised as a food additive in the EU. In previous evaluations by JECFA and the SCF, an ADI of 40 mg/kg bw/day was established based on chronic toxicity in animals. Original reports, previous evaluations, additional […]