Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies
Abstract Aspartame is a methyl ester of a dipeptide used as a synthetic non-nutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the current consumption levels worldwide, the toxicology, and recent epidemiological studies on aspartame. Current use […]
Re-evaluation of acesulfame K with reference to the previous SCF opinion of 1991
Abstract No abstract available. Summary In its re-evaluation of acesulfame K in 2000, the Scientific Committee on Food (SCF) of the European Commission, reaffirmed its previous conclusions that acesulfame potassium (acesulfame K) is safe and without mutagenic or carcinogenic potential. Furthermore, acesulfame K does not induce any other effects of toxicological significance. Furthermore, the Committee […]
Artificial sweeteners and cancer risk in a network of case-control studies
Abstract BACKGROUND: The role of sweeteners on cancer risk has been widely debated over the last few decades. To provide additional information on saccharin and other sweeteners (mainly aspartame), we considered data from a large network of case-control studies. METHODS: An integrated network of case-control studies has been conducted between 1991 and 2004 in Italy. […]
Sweeteners permitted in the European Union: safety aspects
Abstract Sweeteners are substances with a sweet taste. Based on their relative sweetness compared to sucrose, sweeteners are divided into intense or bulk sweeteners. In the past, the Scientific Committee on Food was the scientific guarantor for the safety of food additives (including sweeteners) in use within the European Union (EU). At present, this responsibility […]
Opinion of the Scientific Committee on Food on sucralose
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission concluded that sucralose is safe as a sweetener for general food use and that a full ADI of 0-15mg/kg bw can be established, based on application of a 100-fold safety factor to the overall NOEL of 1500mg/kg bw/day. There is […]
Revised opinion on cyclamic acid and its sodium and calcium salts
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission confirmed that cyclamic acid and its salts are safe and established a full ADI of 0-7 mg/kg bw, expressed as cyclamic acid, for cyclamic acid and its sodium and calcium salts in 2000. Cyclamic acid and its sodium and calcium […]
Opinion on saccharin and its sodium, potassium and calcium salts
Abstract No abstract available. Summary The Scientific Committee on Food (SCF) of the European Commission established a full ADI of 0-5 mg/kg bw for sodium saccharin in 1995 and reconfirmed its safety. Saccharin and its sodium, potassium and calcium salts were first evaluated by the Scientific Committee for Food (SCF) in 1977 when a temporary […]
Non-nutritive Sweeteners for Diabetes Mellitus
Abstract Background: Products sweetened with non-nutritive sweeteners (NNS) are widely available. Many people with type 1 or type 2 diabetes use NNS as a replacement for nutritive sweeteners to control their carbohydrate and energy intake. Health outcomes associated with NNS use in diabetes are unknown. Objectives: To assess the effects of non-nutritive sweeteners in people […]
Nutrition Therapy for Adults with Diabetes or Prediabetes: A Consensus Report
Summary This Consensus Report of the American Diabetes Association (ADA) is intended to provide clinical professionals with evidence-based guidance about individualizing nutrition therapy for adults with diabetes or prediabetes. Nutrition counselling that works toward improving or maintaining glycaemic targets, achieving weight management goals, and improving cardiovascular risk factors (e.g., blood pressure, lipids, etc.) within individualized […]
Consensus of the Latin-American Association of Diabetes on low calorie sweeteners in persons with diabetes
Abstract While non-caloric sweeteners (NCS) are food additives that have been used as a tool to reduce sugar consumption and total energy intake, there is currently a scientific debate around the real benefits of its use. NCS are some of the most evaluated substances in the scientific literature. Their security has been reviewed by international […]